An Artificial Heme Enzyme for Cyclopropanation Reactions

An artificial heme enzyme was created through self‐assembly from hemin and the lactococcal multidrug resistance regulator (LmrR). The crystal structure shows the heme bound inside the hydrophobic pore of the protein, where it appears inaccessible for substrates. However, good catalytic activity and...

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Detalles Bibliográficos
Autores principales: Villarino, Lara, Splan, Kathryn E., Reddem, Eswar, Alonso‐Cotchico, Lur, Gutiérrez de Souza, Cora, Lledós, Agustí, Maréchal, Jean‐Didier, Thunnissen, Andy‐Mark W. H., Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033091/
https://www.ncbi.nlm.nih.gov/pubmed/29719099
http://dx.doi.org/10.1002/anie.201802946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033091/
https://www.ncbi.nlm.nih.gov/pubmed/29719099
http://dx.doi.org/10.1002/anie.201802946

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