Autophosphorylation of the carboxyl‐terminal domain is not required for oncogenic transformation by lung‐cancer derived EGFR mutants

Aberrant activation of cancer‐derived mutants of the epidermal growth factor receptor (EGFR) is closely associated with cancer pathogenesis and is thought to be mediated through multiple tyrosine phosphorylations within the C‐terminal domain. Here, we examined the consequences of the loss of these C...

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Detalles Bibliográficos
Autores principales: Cho, Jeonghee, Kim, Sujin, Du, Jinyan, Meyerson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033109/
https://www.ncbi.nlm.nih.gov/pubmed/29464683
http://dx.doi.org/10.1002/ijc.31332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033109/
https://www.ncbi.nlm.nih.gov/pubmed/29464683
http://dx.doi.org/10.1002/ijc.31332

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