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The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction

A challenge in developing personalized cancer immunotherapies is the prediction of putative cancer‐specific antigens. Currently, predictive algorithms are used to infer binding of peptides to human leukocyte antigen (HLA) heterodimers to aid in the selection of putative epitope targets. One drawback...

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Detalles Bibliográficos
Autores principales: Creech, Amanda L., Ting, Ying S., Goulding, Scott P., Sauld, John F.K., Barthelme, Dominik, Rooney, Michael S., Addona, Terri A., Abelin, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033110/
https://www.ncbi.nlm.nih.gov/pubmed/29314742
http://dx.doi.org/10.1002/pmic.201700259