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Immunoglobulin gene analysis as a tool for investigating human immune responses

The human immunoglobulin repertoire is a hugely diverse set of sequences that are formed by processes of gene rearrangement, heavy and light chain gene assortment, class switching and somatic hypermutation. Early B cell development produces diverse IgM and IgD B cell receptors on the B cell surface,...

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Detalles Bibliográficos
Autores principales: Dunn‐Walters, Deborah, Townsend, Catherine, Sinclair, Emma, Stewart, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033188/
https://www.ncbi.nlm.nih.gov/pubmed/29944755
http://dx.doi.org/10.1111/imr.12659