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Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients

BACKGROUND: Chemerin is a chemoattractant involved in immunity that also functions as an adipokine. Chemerin is secreted as an inactive precursor (chem163S), and its activation requires proteolytic cleavages at its C-terminus, involving proteases in coagulation, fibrinolysis, and inflammation. Previ...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Yamaguchi, Yasuto, Ge, Xiaomei, Robinson, William H., Morser, John, Leung, Lawrence L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033211/
https://www.ncbi.nlm.nih.gov/pubmed/29973268
http://dx.doi.org/10.1186/s13075-018-1615-y