Structurally simple synthetic 1, 4-disubstituted piperidines with high selectivity for resistant Plasmodium falciparum

BACKGROUND: Emergence of resistance to artemisinins and some of their combinations in chemotherapy of clinical malaria has intensified the search for novel safe efficacious antimalarial molecules. Fourteen synthetic 1, 4-disubstituted piperidines with simple molecular structures were evaluated in th...

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Detalles Bibliográficos
Autores principales: Ngemenya, Moses N., Abwenzoh, Grace Ntube, Ikome, Hermia Nalova, Zofou, Denis, Ntie-Kang, Fidele, Efange, Simon M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033213/
https://www.ncbi.nlm.nih.gov/pubmed/29973275
http://dx.doi.org/10.1186/s40360-018-0233-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033213/
https://www.ncbi.nlm.nih.gov/pubmed/29973275
http://dx.doi.org/10.1186/s40360-018-0233-2

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