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Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma
BACKGROUND: We previously reported early on-treatment significant modulation in circulating regulatory T cell (Treg), myeloid derived suppressor cells (MDSC) and antigen-specific type I CD4+ and CD8+ T cells that correlated with clinical outcome in regionally advanced melanoma patients treated with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033230/ https://www.ncbi.nlm.nih.gov/pubmed/29973204 http://dx.doi.org/10.1186/s12967-018-1563-y |