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FlashFry: a fast and flexible tool for large-scale CRISPR target design

BACKGROUND: Genome-wide knockout studies, noncoding deletion scans, and other large-scale studies require a simple and lightweight framework that can quickly discover and score thousands of candidate CRISPR guides targeting an arbitrary DNA sequence. While several CRISPR web applications exist, ther...

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Detalles Bibliográficos
Autores principales: McKenna, Aaron, Shendure, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033233/
https://www.ncbi.nlm.nih.gov/pubmed/29976198
http://dx.doi.org/10.1186/s12915-018-0545-0