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FlashFry: a fast and flexible tool for large-scale CRISPR target design
BACKGROUND: Genome-wide knockout studies, noncoding deletion scans, and other large-scale studies require a simple and lightweight framework that can quickly discover and score thousands of candidate CRISPR guides targeting an arbitrary DNA sequence. While several CRISPR web applications exist, ther...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033233/ https://www.ncbi.nlm.nih.gov/pubmed/29976198 http://dx.doi.org/10.1186/s12915-018-0545-0 |