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Human mesenchymal stromal cells inhibit platelet activation and aggregation involving CD73-converted adenosine

BACKGROUND: Mesenchymal stromal cells (MSCs) are promising cell therapy candidates. Clinical application is considered safe. However, minor side effects have included thromboembolism and instant blood-mediated inflammatory reactions suggesting an effect of MSC infusion on hemostasis. Previous studie...

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Detalles Bibliográficos
Autores principales: Netsch, P., Elvers-Hornung, S., Uhlig, S., Klüter, H., Huck, V., Kirschhöfer, F., Brenner-Weiß, G., Janetzko, K., Solz, H., Wuchter, P., Bugert, P., Bieback, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033237/
https://www.ncbi.nlm.nih.gov/pubmed/29973267
http://dx.doi.org/10.1186/s13287-018-0936-8