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CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes
BACKGROUND: In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan. Misregulated activation of primordial follicles leads to various ovarian diseases, such as premature ovarian insufficiency (POI). Althoug...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033292/ https://www.ncbi.nlm.nih.gov/pubmed/29976179 http://dx.doi.org/10.1186/s12915-018-0541-4 |