Cargando…

CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

BACKGROUND: In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan. Misregulated activation of primordial follicles leads to various ovarian diseases, such as premature ovarian insufficiency (POI). Althoug...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Hao, Zhang, Jiawei, Wen, Jia, Wang, Yibo, Niu, Wanbao, Teng, Zhen, Zhao, Tongtong, Dai, Yanli, Zhang, Yan, Wang, Chao, Qin, Yingying, Xia, Guoliang, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033292/
https://www.ncbi.nlm.nih.gov/pubmed/29976179
http://dx.doi.org/10.1186/s12915-018-0541-4