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Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model

Recent reports have revealed the impact of a western diet containing large amounts of fructose on the pathogenesis of non-alcoholic steatohepatitis (NASH). Fructose exacerbates hepatic inflammation in NASH by inducing increasing intestinal permeability. However, it is not clear whether fructose cont...

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Detalles Bibliográficos
Autores principales: Seki, Kenichiro, Kitade, Mitsuteru, Nishimura, Norihisa, Kaji, Kosuke, Asada, Kiyoshi, Namisaki, Tadashi, Moriya, Kei, Kawaratani, Hideto, Okura, Yasushi, Takaya, Hiroaki, Sawada, Yasuhiko, Sato, Shinya, Nakanishi, Keisuke, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033350/
https://www.ncbi.nlm.nih.gov/pubmed/29983886
http://dx.doi.org/10.18632/oncotarget.25587