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Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus

Intratumoral therapy with oncolytic viruses is increasingly being explored as a strategy to potentiate an immune response against cancer, but it remains unknown whether such therapy should be restricted to cancers sensitive to virus-mediated lysis. Using Newcastle Disease Virus (NDV) as a model, we...

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Detalles Bibliográficos
Autores principales: Oseledchyk, Anton, Ricca, Jacob M., Gigoux, Mathieu, Ko, Brian, Redelman-Sidi, Gil, Walther, Tyler, Liu, Cailian, Iyer, Gopa, Merghoub, Taha, Wolchok, Jedd D., Zamarin, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033351/
https://www.ncbi.nlm.nih.gov/pubmed/29983890
http://dx.doi.org/10.18632/oncotarget.25614