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Induction chemotherapy reduces extracellular heat shock protein 72 levels, inflammation, lipoperoxidation and changes insulin sensitivity in children and adolescents newly diagnosed with acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) is associated with higher levels of pro-inflammatory cytokines and oxidative stress. Recently, the levels of extracellular heat shock protein 72 (eHSP72) were found to be elevated in ALL, and its elevation associated with poor prognosis. Therefore, cons...

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Detalles Bibliográficos
Autores principales: Trussardi Fayh, Ana Paula, de Carvalho Gomes, Camila, Schroeder, Helena Trevisan, Henrique de Lemos Muller, Carlos, Maria de Araújo Moura Lemos, Telma, Krause, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033368/
https://www.ncbi.nlm.nih.gov/pubmed/29983896
http://dx.doi.org/10.18632/oncotarget.25609