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SAFlex: A structural alphabet extension to integrate protein structural flexibility and missing data information

In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of missing residues or uncertainties. An SA aims t...

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Detalles Bibliográficos
Autores principales: Allam, Ikram, Flatters, Delphine, Caumes, Géraldine, Regad, Leslie, Delos, Vincent, Nuel, Gregory, Camproux, Anne-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033379/
https://www.ncbi.nlm.nih.gov/pubmed/29975698
http://dx.doi.org/10.1371/journal.pone.0198854