Genetics instability of wtAAV2 genome and AAV promoter activities in the Baculovirus/Sf9 cells system

The human Adeno-Associated Virus serotype 2 (wtAAV2) is a common non-pathological virus and its recombinant form (rAAV) is widely used as gene therapy vector. Although rAAVs are routinely produced in the Baculovirus/Sf9 cell system, wtAAV2 has never been studied in this context. We tried to produce...

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Detalles Bibliográficos
Autores principales: Savy, Adrien, Kaikkonen, Minna U., Léger, Adrien, Dickx, Yohann, Galibert, Lionel, Merten, Otto-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033426/
https://www.ncbi.nlm.nih.gov/pubmed/29975713
http://dx.doi.org/10.1371/journal.pone.0199866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033426/
https://www.ncbi.nlm.nih.gov/pubmed/29975713
http://dx.doi.org/10.1371/journal.pone.0199866

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