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Genetics instability of wtAAV2 genome and AAV promoter activities in the Baculovirus/Sf9 cells system
The human Adeno-Associated Virus serotype 2 (wtAAV2) is a common non-pathological virus and its recombinant form (rAAV) is widely used as gene therapy vector. Although rAAVs are routinely produced in the Baculovirus/Sf9 cell system, wtAAV2 has never been studied in this context. We tried to produce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033426/ https://www.ncbi.nlm.nih.gov/pubmed/29975713 http://dx.doi.org/10.1371/journal.pone.0199866 |