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ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

Dynamic post-transcriptional control of RNA expression by RNA-binding proteins (RBPs) is critical during immune response. ZFP36 RBPs are prominent inflammatory regulators linked to autoimmunity and cancer, but functions in adaptive immunity are less clear. We used HITS-CLIP to define ZFP36 targets i...

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Detalles Bibliográficos
Autores principales: Moore, Michael J, Blachere, Nathalie E, Fak, John J, Park, Christopher Y, Sawicka, Kirsty, Parveen, Salina, Zucker-Scharff, Ilana, Moltedo, Bruno, Rudensky, Alexander Y, Darnell, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033538/
https://www.ncbi.nlm.nih.gov/pubmed/29848443
http://dx.doi.org/10.7554/eLife.33057