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Dynamic allostery can drive cold adaptation in enzymes

Adaptation of organisms to environmental niches is a hallmark of evolution. One prevalent example is that of thermal adaptation, wherein two descendants evolve at different temperature extremes(1,2). Underlying the physiological differences between such organisms are changes in enzymes catalyzing es...

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Detalles Bibliográficos
Autores principales: Saavedra, Harry G., Wrabl, James O., Anderson, Jeremy A., Li, Jing, Hilser, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033628/
https://www.ncbi.nlm.nih.gov/pubmed/29875414
http://dx.doi.org/10.1038/s41586-018-0183-2