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Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates kidney injury in murine models of obesity and diabetes mellitus

AIM: To investigate the role of glucagon-like peptide-1 (GLP-1)/glucagon receptors coagonist on renal dysfunction associated with diabetes and obesity. METHODS: Chronic high-fat diet fed C57BL/6J mice, streptozotocin-treated high-fat diet fed C57BL/6J mice and diabetic C57BLKS/J db/db mice were used...

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Detalles Bibliográficos
Autores principales: Patel, Vishal J, Joharapurkar, Amit A, Kshirsagar, Samadhan G, Sutariya, Brijesh K, Patel, Maulik S, Patel, Hiren M, Pandey, Dheerendra K, Bahekar, Rajesh H, Jain, Mukul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033704/
https://www.ncbi.nlm.nih.gov/pubmed/29988851
http://dx.doi.org/10.4239/wjd.v9.i6.80