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Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders

Glutamate is the predominant excitatory neurotransmitter in the human brain and it has been shown that prolonged activation of the glutamatergic system leads to nerve damage and cell death. Following release from the pre-synaptic neuron and synaptic transmission, glutamate is either taken up into th...

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Detalles Bibliográficos
Autores principales: Parkin, Georgia M, Udawela, Madhara, Gibbons, Andrew, Dean, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033743/
https://www.ncbi.nlm.nih.gov/pubmed/29988908
http://dx.doi.org/10.5498/wjp.v8.i2.51