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DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia

The spatio-temporal regulation of genes involved in the synthesis and degradation of D-serine and D-aspartate such as serine racemase (SR), D-amino acid oxidase (DAO), G72 and D-aspartate oxidase (DDO), play pivotal roles in determining the correct levels of these D-amino acids in the human brain. H...

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Detalles Bibliográficos
Autores principales: Keller, Simona, Punzo, Daniela, Cuomo, Mariella, Affinito, Ornella, Coretti, Lorena, Sacchi, Silvia, Florio, Ermanno, Lembo, Francesca, Carella, Massimo, Copetti, Massimiliano, Cocozza, Sergio, Balu, Darrick T., Errico, Francesco, Usiello, Alessandro, Chiariotti, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033866/
https://www.ncbi.nlm.nih.gov/pubmed/29976992
http://dx.doi.org/10.1038/s41598-018-28332-x