Dietary fat-associated osteoarthritic chondrocytes gain resistance to lipotoxicity through PKCK2/STAMP2/FSP27

Free fatty acids (FFAs), which are elevated with metabolic syndrome, are considered the principal offender exerting lipotoxicity. Few previous studies have reported a causal relationship between FFAs and osteoarthritis pathogenesis. However, the molecular mechanism by which FFAs exert lipotoxicity a...

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Detalles Bibliográficos
Autores principales: Lee, Sung Won, Rho, Jee Hyun, Lee, Sang Yeob, Chung, Won Tae, Oh, Yoo Jin, Kim, Jung Ha, Yoo, Seung Hee, Kwon, Woo Young, Bae, Ju Yong, Seo, Su Young, Sun, Hokeun, Kim, Hye Young, Yoo, Young Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033867/
https://www.ncbi.nlm.nih.gov/pubmed/30002945
http://dx.doi.org/10.1038/s41413-018-0020-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033867/
https://www.ncbi.nlm.nih.gov/pubmed/30002945
http://dx.doi.org/10.1038/s41413-018-0020-0

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