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Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors

Megakaryocytes (MKs) are the precursors of platelets (PLTs) and may be used for PLT production in vivo or in vitro, as well as a source for PLT-derived growth factors. Induced pluripotent stem cells represent an unlimited cell source for the in vitro production of MKs. This study aimed at developing...

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Detalles Bibliográficos
Autores principales: Eicke, Dorothee, Baigger, Anja, Schulze, Kai, Latham, Sharissa L., Halloin, Caroline, Zweigerdt, Robert, Guzman, Carlos A., Blasczyk, Rainer, Figueiredo, Constança
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033877/
https://www.ncbi.nlm.nih.gov/pubmed/29977045
http://dx.doi.org/10.1038/s41598-018-28459-x