Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion. Here, we show that CSRP2, an invadopodial actin bundling protein, is upr...

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Detalles Bibliográficos
Autores principales: Hoffmann, Céline, Mao, Xianqing, Brown-Clay, Joshua, Moreau, Flora, Al Absi, Antoun, Wurzer, Hannah, Sousa, Barbara, Schmitt, Fernando, Berchem, Guy, Janji, Bassam, Thomas, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033879/
https://www.ncbi.nlm.nih.gov/pubmed/29976963
http://dx.doi.org/10.1038/s41598-018-28637-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033879/
https://www.ncbi.nlm.nih.gov/pubmed/29976963
http://dx.doi.org/10.1038/s41598-018-28637-x

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