The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

There is no established medical therapy to treat biliary fibrosis resulting from chronic inflammation in the biliary tree. We have recently shown that liver-specific over-expression of angiotensin converting enzyme 2 (ACE2) of the renin angiotensin system (RAS) ameliorated liver fibrosis in mice. Di...

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Detalles Bibliográficos
Autores principales: Rajapaksha, Indu G., Mak, Kai Y., Huang, Ping, Burrell, Louise M., Angus, Peter W., Herath, Chandana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033899/
https://www.ncbi.nlm.nih.gov/pubmed/29977014
http://dx.doi.org/10.1038/s41598-018-28490-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033899/
https://www.ncbi.nlm.nih.gov/pubmed/29977014
http://dx.doi.org/10.1038/s41598-018-28490-y

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