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Exposure to podophyllotoxin inhibits oocyte meiosis by disturbing meiotic spindle formation

Podophyllotoxin is used as medical cream which is widely applied to genital warts and molluscum contagiosum. Although previous study showed that podophyllotoxin had minimal toxicity, it was forbidden to use during pregnancy since it might be toxic to the embryos. In present study we used mouse as th...

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Detalles Bibliográficos
Autores principales: Hu, Lin-Lin, Zhou, Xin, Zhang, Hao-Lin, Wu, Lan-Lan, Tang, Lian-Sheng, Chen, Ling-Li, Duan, Jin-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033908/
https://www.ncbi.nlm.nih.gov/pubmed/29976965
http://dx.doi.org/10.1038/s41598-018-28544-1