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Exposure to podophyllotoxin inhibits oocyte meiosis by disturbing meiotic spindle formation
Podophyllotoxin is used as medical cream which is widely applied to genital warts and molluscum contagiosum. Although previous study showed that podophyllotoxin had minimal toxicity, it was forbidden to use during pregnancy since it might be toxic to the embryos. In present study we used mouse as th...
Autores principales: | Hu, Lin-Lin, Zhou, Xin, Zhang, Hao-Lin, Wu, Lan-Lan, Tang, Lian-Sheng, Chen, Ling-Li, Duan, Jin-Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033908/ https://www.ncbi.nlm.nih.gov/pubmed/29976965 http://dx.doi.org/10.1038/s41598-018-28544-1 |
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