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Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina

In vertebrate retinal progenitor cells, the proneural factor Atoh7 exhibits a dynamic tissue and cellular expression pattern. Although the resulting Atoh7 retinal lineage contains all seven major cell types, only retinal ganglion cells require Atoh7 for proper differentiation. Such specificity neces...

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Detalles Bibliográficos
Autores principales: Miesfeld, Joel B., Moon, Myung-soon, Riesenberg, Amy N., Contreras, Ashley N., Kovall, Rhett A., Brown, Nadean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033939/
https://www.ncbi.nlm.nih.gov/pubmed/29977079
http://dx.doi.org/10.1038/s41598-018-28420-y