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Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

The PTEN gene encodes for the phosphatase and tensin homolog; it is a tumor suppressor gene that is among the most frequently inactivated genes throughout the human cancer spectrum. The most recent sequencing approaches have allowed the identification of PTEN genomic alterations, including deletion,...

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Detalles Bibliográficos
Autores principales: Poluri, Raghavendra Tejo Karthik, Audet-Walsh, Étienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033966/
https://www.ncbi.nlm.nih.gov/pubmed/30009155
http://dx.doi.org/10.3389/fonc.2018.00246