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Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis
Induced expression of serum amyloid A (SAA) is a hallmark of many inflammatory diseases, but whether SAA exacerbates inflammation or protects tissues against injury remains unclear. In dextran sulfate sodium (DSS)-induced colitis, SAA3 is the predominant isoform of inducible SAA proteins that also i...
Autores principales: | Zhang, Gufang, Liu, Jin, Wu, Lehao, Fan, Yu, Sun, Lei, Qian, Feng, Chen, Daijie, Ye, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033967/ https://www.ncbi.nlm.nih.gov/pubmed/30008720 http://dx.doi.org/10.3389/fimmu.2018.01503 |
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