Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis

Induced expression of serum amyloid A (SAA) is a hallmark of many inflammatory diseases, but whether SAA exacerbates inflammation or protects tissues against injury remains unclear. In dextran sulfate sodium (DSS)-induced colitis, SAA3 is the predominant isoform of inducible SAA proteins that also i...

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Detalles Bibliográficos
Autores principales: Zhang, Gufang, Liu, Jin, Wu, Lehao, Fan, Yu, Sun, Lei, Qian, Feng, Chen, Daijie, Ye, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033967/
https://www.ncbi.nlm.nih.gov/pubmed/30008720
http://dx.doi.org/10.3389/fimmu.2018.01503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033967/
https://www.ncbi.nlm.nih.gov/pubmed/30008720
http://dx.doi.org/10.3389/fimmu.2018.01503

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