The development of colitis in Il10(−/−) mice is dependent on IL-22

Mice deficient in the IL-10 pathway are the most widely-used models of intestinal immunopathology.IL-17A is strongly implicated in gut disease in mice and humans, but conflicting evidence has drawn IL-17’s role in the gut into question.IL-22 regulates antimicrobial and repair activities of intestina...

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Detalles Bibliográficos
Autores principales: Gunasekera, Dilini C., Ma, Jinxia, Vacharathit, Vimvara, Shah, Palak, Ramakrishnan, Amritha, Uprety, Priyanka, Shen, Zeli, Sheh, Alexander, Brayton, Cory F., Whary, Mark T., Fox, James G., Bream, Jay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566780/
https://www.ncbi.nlm.nih.gov/pubmed/31932715
http://dx.doi.org/10.1038/s41385-019-0252-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566780/
https://www.ncbi.nlm.nih.gov/pubmed/31932715
http://dx.doi.org/10.1038/s41385-019-0252-3

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