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Pharmacological Manipulation of DNA Methylation in Adult Female Rats Normalizes Behavioral Consequences of Early-Life Maltreatment

Exposure to adversity early in development alters brain and behavioral trajectories. Data continue to accumulate that epigenetic mechanisms are a mediating factor between early-life adversity and adult behavioral phenotypes. Previous work from our laboratory has shown that female Long-Evans rats exp...

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Detalles Bibliográficos
Autores principales: Keller, Samantha M., Doherty, Tiffany S., Roth, Tania L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034089/
https://www.ncbi.nlm.nih.gov/pubmed/30008666
http://dx.doi.org/10.3389/fnbeh.2018.00126