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Inflammation leads through PGE/EP (3) signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes

The myocyte enhancer factor 2 (MEF2) regulates transcription in cardiac myocytes and adverse remodeling of adult hearts. Activators of G protein‐coupled receptors (GPCRs) have been reported to activate MEF2, but a comprehensive analysis of GPCR activators that regulate MEF2 has to our knowledge not...

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Detalles Bibliográficos
Autores principales: Tóth, András D, Schell, Richard, Lévay, Magdolna, Vettel, Christiane, Theis, Philipp, Haslinger, Clemens, Alban, Felix, Werhahn, Stefanie, Frischbier, Lina, Krebs‐Haupenthal, Jutta, Thomas, Dominique, Gröne, Hermann‐Josef, Avkiran, Metin, Katus, Hugo A, Wieland, Thomas, Backs, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034133/
https://www.ncbi.nlm.nih.gov/pubmed/29907596
http://dx.doi.org/10.15252/emmm.201708536