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Structural Basis for the Catalytic Mechanism of Ethylenediamine-N,N′-disuccinic Acid Lyase, a Carbon–Nitrogen Bond-Forming Enzyme with a Broad Substrate Scope

[Image: see text] The natural aminocarboxylic acid product ethylenediamine-N,N′-disuccinic acid [(S,S)-EDDS] is able to form a stable complex with metal ions, making it an attractive biodegradable alternative for the synthetic metal chelator ethylenediaminetetraacetic acid (EDTA), which is currently...

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Detalles Bibliográficos
Autores principales: Poddar, Harshwardhan, de Villiers, Jandré, Zhang, Jielin, Puthan Veetil, Vinod, Raj, Hans, Thunnissen, Andy-Mark W. H., Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034166/
https://www.ncbi.nlm.nih.gov/pubmed/29741885
http://dx.doi.org/10.1021/acs.biochem.8b00406