Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects

Altered metabolism of biometals in the brain is a key feature of Alzheimer's disease, and biometal interactions with amyloid-β are linked to amyloid plaque formation. Iron-rich aggregates, including evidence for the mixed-valence iron oxide magnetite, are associated with amyloid plaques. To tes...

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Detalles Bibliográficos
Autores principales: Everett, James, Collingwood, Joanna F., Tjendana-Tjhin, Vindy, Brooks, Jake, Lermyte, Frederik, Plascencia-Villa, Germán, Hands-Portman, Ian, Dobson, Jon, Perry, George, Telling, Neil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034173/
https://www.ncbi.nlm.nih.gov/pubmed/29688240
http://dx.doi.org/10.1039/c7nr06794a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034173/
https://www.ncbi.nlm.nih.gov/pubmed/29688240
http://dx.doi.org/10.1039/c7nr06794a

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