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Next-generation sequencing profiling of mitochondrial genomes in gout

BACKGROUND: Accumulating evidence implicates mitochondrial DNA (mtDNA) alleles, which are independent of the nuclear genome, in disease, especially in human metabolic diseases. However, this area of investigation has lagged behind in researching the nuclear alleles in complex traits, for example, in...

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Detalles Bibliográficos
Autores principales: Tseng, Chia-Chun, Chen, Chung-Jen, Yen, Jeng-Hsien, Huang, Hsi-Yuan, Chang, Jan-Gowth, Chang, Shun-Jen, Liao, Wei-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034246/
https://www.ncbi.nlm.nih.gov/pubmed/29976239
http://dx.doi.org/10.1186/s13075-018-1637-5