Mediation analysis to understand genetic relationships between habitual coffee intake and gout

BACKGROUND: Increased coffee intake is associated with reduced serum urate concentrations and lower risk of gout. Specific alleles of the GCKR, ABCG2, MLXIPL, and CYP1A2 genes have been associated with both reduced coffee intake and increased serum urate in separate genome-wide association studies (...

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Detalles Bibliográficos
Autores principales: Hutton, Joseph, Fatima, Tahzeeb, Major, Tanya J., Topless, Ruth, Stamp, Lisa K., Merriman, Tony R., Dalbeth, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034252/
https://www.ncbi.nlm.nih.gov/pubmed/29976226
http://dx.doi.org/10.1186/s13075-018-1629-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034252/
https://www.ncbi.nlm.nih.gov/pubmed/29976226
http://dx.doi.org/10.1186/s13075-018-1629-5

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