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TROP2 methylation and expression in tamoxifen-resistant breast cancer

BACKGROUND: The DNA methyltransferase 1 inhibitor, 5-Aza-2′-deoxycytidine (5-Aza-dC) is a potential treatment for breast cancer. However, not all breast tumors will respond similarly to treatment with 5-Aza-dC, and little is known regarding the response of hormone-resistant breast cancers to 5-Aza-d...

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Detalles Bibliográficos
Autores principales: Zimmers, Stephanie M., Browne, Eva P., Williams, Kristin E., Jawale, Rahul M., Otis, Christopher N., Schneider, Sallie S., Arcaro, Kathleen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034260/
https://www.ncbi.nlm.nih.gov/pubmed/30002602
http://dx.doi.org/10.1186/s12935-018-0589-9