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Introduction of F446I mutation in the K13 propeller gene leads to increased ring survival rates in Plasmodium falciparum isolates

BACKGROUND: Mutations in the Plasmodium falciparum k13 gene are associated with artemisinin (ART) resistance. However, it is unclear whether the F446I mutation, the most prevalent allele at the China–Myanmar border and north of Myanmar, is associated with ART resistance. Therefore, the aim of this s...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Huang, Yufu, Zhao, Yuemeng, Ye, Run, Zhang, Dongmei, Pan, Weiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034266/
https://www.ncbi.nlm.nih.gov/pubmed/29976207
http://dx.doi.org/10.1186/s12936-018-2396-0