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3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model

BACKGROUND: Sentinel lymph node metastasis is a common and early event in the metastatic process of head and neck squamous cell carcinoma (HNSCC) and is the most powerful prognostic factor for survival of HNSCC patients. 3-O-acetyloleanolic acid (3AOA), a pentacyclic triterpenoid compound isolated f...

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Detalles Bibliográficos
Autores principales: Hwang-Bo, Jeon, Bae, Mun Gyeong, Park, Jong-Hwa, Chung, In Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034267/
https://www.ncbi.nlm.nih.gov/pubmed/29976150
http://dx.doi.org/10.1186/s12885-018-4630-0