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DDIT4 promotes gastric cancer proliferation and tumorigenesis through the p53 and MAPK pathways

BACKGROUND: Gastric cancer (GC) is one of the most common malignancies worldwide, particularly in China. DNA damage-inducible transcript 4 (DDIT4) is a mammalian target of rapamycin inhibitor and is induced by various cellular stresses; however, its critical role in GC remains poorly understood. The...

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Detalles Bibliográficos
Autores principales: Du, Feng, Sun, Lina, Chu, Yi, Li, Tingyu, Lei, Chao, Wang, Xin, Jiang, Mingzuo, Min, Yali, Lu, Yuanyuan, Zhao, Xiaodi, Nie, Yongzhan, Fan, Daiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034313/
https://www.ncbi.nlm.nih.gov/pubmed/29976242
http://dx.doi.org/10.1186/s40880-018-0315-y