Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays

BACKGROUND: The ability of HIV-1 to integrate into the genomes of quiescent host immune cells, establishing a long-lived latent viral reservoir (LVR), is the primary obstacle to curing these infections. Quantitative viral outgrowth assays (QVOAs) are the gold standard for estimating the size of the...

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Detalles Bibliográficos
Autores principales: Poon, Art F. Y., Prodger, Jessica L., Lynch, Briana A., Lai, Jun, Reynolds, Steven J., Kasule, Jingo, Capoferri, Adam A., Lamers, Susanna L., Rodriguez, Christopher W., Bruno, Daniel, Porcella, Stephen F., Martens, Craig, Quinn, Thomas C., Redd, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034329/
https://www.ncbi.nlm.nih.gov/pubmed/29976219
http://dx.doi.org/10.1186/s12977-018-0426-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034329/
https://www.ncbi.nlm.nih.gov/pubmed/29976219
http://dx.doi.org/10.1186/s12977-018-0426-1

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