Cargando…

Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays

BACKGROUND: The ability of HIV-1 to integrate into the genomes of quiescent host immune cells, establishing a long-lived latent viral reservoir (LVR), is the primary obstacle to curing these infections. Quantitative viral outgrowth assays (QVOAs) are the gold standard for estimating the size of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poon, Art F. Y., Prodger, Jessica L., Lynch, Briana A., Lai, Jun, Reynolds, Steven J., Kasule, Jingo, Capoferri, Adam A., Lamers, Susanna L., Rodriguez, Christopher W., Bruno, Daniel, Porcella, Stephen F., Martens, Craig, Quinn, Thomas C., Redd, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034329/ https://www.ncbi.nlm.nih.gov/pubmed/29976219 http://dx.doi.org/10.1186/s12977-018-0426-1

Ejemplares similares

A15 Archived ART resistance in the latent reservoir of virally suppressed Ugandans
por: Capoferri, A A, et al.
Publicado: (2019)

Quantifying the clonality and dynamics of the within-host HIV-1 latent reservoir
por: Ferreira, Roux-Cil, et al.
Publicado: (2021)

Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen
por: Ferreira, Roux-Cil, et al.
Publicado: (2023)

Dating reservoir formation in virologically suppressed people living with HIV-1 in Rakai, Uganda
por: Kankaka, Edward Nelson, et al.
Publicado: (2023)

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
por: Laird, Gregory M., et al.
Publicado: (2013)

A highly reproducible quantitative viral outgrowth assay for the measurement of the replication-competent latent HIV-1 reservoir
por: Fun, Axel, et al.
Publicado: (2017)

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size
por: Rosenbloom, Daniel I. S., et al.
Publicado: (2019)

Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size
por: Stone, Mars, et al.
Publicado: (2020)

The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs
por: Metcalf Pate, Kelly A., et al.
Publicado: (2017)

HIV-1 Nef Protein Structures Associated with Brain Infection and Dementia Pathogenesis
por: Lamers, Susanna L., et al.
Publicado: (2011)

Proliferation of latently infected CD4(+) T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
por: Hosmane, Nina N., et al.
Publicado: (2017)

The reservoir of latent HIV
por: Chen, Jing, et al.
Publicado: (2022)

The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir
por: Benner, Sarah E., et al.
Publicado: (2022)

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay
por: Stuelke, Erin L., et al.
Publicado: (2020)

Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1
por: Rosenbloom, Daniel I. S., et al.
Publicado: (2015)

336. Developing a Protein Signature of Early Latent Tuberculosis Infection.
por: Bark, Charles, et al.
Publicado: (2022)

The HIV nef protein within ARL is genetically and structurally distinct from those in the brain of patients with HAD
por: Lamers, Susanna L, et al.
Publicado: (2010)

A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses
por: Bruner, Katherine M., et al.
Publicado: (2019)

Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays
por: Kuzmichev, Yury V., et al.
Publicado: (2023)

Heterogeneity of HIV-1 latent reservoirs
por: Zhao, Jia-Cong, et al.
Publicado: (2020)

Eradication of HIV-1 latent reservoirs through therapeutic vaccination
por: Pankrac, Joshua, et al.
Publicado: (2017)

Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions
por: Hill, Alison L., et al.
Publicado: (2016)

How to Define the Latent Reservoir: Tools of the Trade
por: Barton, Kirston M., et al.
Publicado: (2016)

HIV-1 latent reservoir: size matters
por: Hodel, Flavia, et al.
Publicado: (2016)

HCMV Antivirals and Strategies to Target the Latent Reservoir
por: Perera, Marianne R., et al.
Publicado: (2021)

Surgery Triggers Outgrowth of Latent Distant Disease in Breast Cancer: An Inconvenient Truth?
por: Retsky, Michael, et al.
Publicado: (2010)

HIV-Positive Liver Transplant Does not Alter the Latent Viral Reservoir in Recipients With Antiretroviral Therapy-Suppressed HIV
por: Benner, Sarah E, et al.
Publicado: (2023)

Block and Lock HIV Cure Strategies to Control the Latent Reservoir
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2020)

Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein
por: Krishna, B. A., et al.
Publicado: (2017)

The HIV-1 latent reservoir is largely sensitive to circulating T cells
por: Warren, Joanna A, et al.
Publicado: (2020)

Innovations in the quantitative virus outgrowth assay and its use in clinical trials
por: Norton, Nicholas J., et al.
Publicado: (2017)

Targeting the latent reservoir to achieve functional HIV cure
por: Cary, Daniele C., et al.
Publicado: (2016)

Establishment and stability of the latent HIV-1 DNA reservoir
por: Brodin, Johanna, et al.
Publicado: (2016)

Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1
por: Sanz, Marta, et al.
Publicado: (2023)

Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1
por: Sanz, Marta, et al.
Publicado: (2023)

Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir
por: Wang, Zheng, et al.
Publicado: (2018)

Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection
por: Wodarz, Dominik, et al.
Publicado: (2017)

Mining for humoral correlates of HIV control and latent reservoir size
por: Das, Jishnu, et al.
Publicado: (2020)

The forces driving clonal expansion of the HIV-1 latent reservoir
por: Liu, Runxia, et al.
Publicado: (2020)

Measuring the size and decay dynamics of the HIV-1 latent reservoir
por: Liu, Runxia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1ou7dqg2hnbb0ifeck7h055822