Cargando…

Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases

BACKGROUND: Syndecan-1 (Sdc1), a cell surface heparan sulfate proteoglycan normally expressed primarily by epithelia and plasma cells, is aberrantly induced in stromal fibroblasts of breast carcinomas. Stromal fibroblast-derived Sdc1 participates in paracrine growth stimulation of breast carcinoma c...

Descripción completa

Detalles Bibliográficos
Autores principales: Chute, Colleen, Yang, Xinhai, Meyer, Kristy, Yang, Ning, O’Neil, Keelin, Kasza, Ildiko, Eliceiri, Kevin, Alexander, Caroline, Friedl, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034333/
https://www.ncbi.nlm.nih.gov/pubmed/29976229
http://dx.doi.org/10.1186/s13058-018-0995-x