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Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases
BACKGROUND: Syndecan-1 (Sdc1), a cell surface heparan sulfate proteoglycan normally expressed primarily by epithelia and plasma cells, is aberrantly induced in stromal fibroblasts of breast carcinomas. Stromal fibroblast-derived Sdc1 participates in paracrine growth stimulation of breast carcinoma c...
Autores principales: | Chute, Colleen, Yang, Xinhai, Meyer, Kristy, Yang, Ning, O’Neil, Keelin, Kasza, Ildiko, Eliceiri, Kevin, Alexander, Caroline, Friedl, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034333/ https://www.ncbi.nlm.nih.gov/pubmed/29976229 http://dx.doi.org/10.1186/s13058-018-0995-x |
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