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AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer. The D-arabinan segment is a highly branched component of AG and is assembled in a step-wise fashion by a variety o...

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Detalles Bibliográficos
Autores principales: Alderwick, Luke J., Birch, Helen L., Krumbach, Karin, Bott, Michael, Eggeling, Lothar, Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034362/
https://www.ncbi.nlm.nih.gov/pubmed/29998212
http://dx.doi.org/10.1016/j.tcsw.2017.10.001