Cargando…

AftD functions as an α1 → 5 arabinofuranosyltransferase involved in the biosynthesis of the mycobacterial cell wall core

Arabinogalactan (AG) is an essential structural macromolecule present in the cell wall of Mycobacterium tuberculosis, serving to connect peptidoglycan with the outer mycolic acid layer. The D-arabinan segment is a highly branched component of AG and is assembled in a step-wise fashion by a variety o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alderwick, Luke J., Birch, Helen L., Krumbach, Karin, Bott, Michael, Eggeling, Lothar, Besra, Gurdyal S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034362/ https://www.ncbi.nlm.nih.gov/pubmed/29998212 http://dx.doi.org/10.1016/j.tcsw.2017.10.001

Ejemplares similares

Biosynthesis of mycobacterial arabinogalactan: identification of a novel α(1→3) arabinofuranosyltransferase
por: Birch, Helen L, et al.
Publicado: (2008)

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis
por: Jankute, Monika, et al.
Publicado: (2018)

Benzothiazinones Mediate Killing of Corynebacterineae by Blocking Decaprenyl Phosphate Recycling Involved in Cell Wall Biosynthesis
por: Grover, Shipra, et al.
Publicado: (2014)

Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan
por: Jankute, Monika, et al.
Publicado: (2016)

Enhanced immunogenicity of Mycobacterium bovis BCG through CRISPRi mediated depletion of AftC
por: Madduri, Bala T.S.A., et al.
Publicado: (2022)

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target
por: ABRAHAMS, KATHERINE A., et al.
Publicado: (2018)

Elucidation of a protein-protein interaction network involved in Corynebacterium glutamicum cell wall biosynthesis as determined by bacterial two-hybrid analysis
por: Jankute, Monika, et al.
Publicado: (2014)

Identification of an α(1→6) mannopyranosyltransferase (MptA), involved in Corynebacterium glutamicum lipomanann biosynthesis, and identification of its orthologue in Mycobacterium tuberculosis
por: Mishra, Arun K, et al.
Publicado: (2007)

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching
por: Mishra, Arun K, et al.
Publicado: (2011)

Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis
por: Gong, Yicheng, et al.
Publicado: (2023)

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase
por: Alderwick, Luke J, et al.
Publicado: (2011)

MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria
por: Varela, Cristian, et al.
Publicado: (2012)

Structural characterization of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiA mutant
por: Tatituri, Raju Venkata Veera, et al.
Publicado: (2007)

Acceptor Substrate Discrimination in Phosphatidyl-myo-inositol Mannoside Synthesis: STRUCTURAL AND MUTATIONAL ANALYSIS OF MANNOSYLTRANSFERASE CORYNEBACTERIUM GLUTAMICUM PimB′
por: Batt, Sarah M., et al.
Publicado: (2010)

The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module
por: Alderwick, Luke J., et al.
Publicado: (2011)

Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall
por: Batt, Sarah M., et al.
Publicado: (2020)

Mycobacterial drug discovery
por: Abrahams, Katherine A., et al.
Publicado: (2020)

Differential Arabinan Capping of Lipoarabinomannan Modulates Innate Immune Responses and Impacts T Helper Cell Differentiation
por: Mishra, Arun K., et al.
Publicado: (2012)

Identification of a novel α(1→6) mannopyranosyltransferase MptB from Corynebacterium glutamicum by deletion of a conserved gene, NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant
por: Mishra, Arun K, et al.
Publicado: (2008)

Synthesis and recycling of the mycobacterial cell envelope
por: Abrahams, Katherine A, et al.
Publicado: (2021)

A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level
por: Binder, Stephan, et al.
Publicado: (2012)

Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB′ mutant
por: Mishra, Arun K., et al.
Publicado: (2008)

Controls and the AFT Tool
por: Roderick, C, et al.
Publicado: (2019)

Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis
por: Burke, Christopher, et al.
Publicado: (2019)

Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria
por: Kanvatirth, Panchali, et al.
Publicado: (2019)

Loss of a Mycobacterial Gene Encoding a Reductase Leads to an Altered Cell Wall Containing β-oxo- Mycolic Acid Analogs and Accumulation of Ketones
por: Bhatt, Apoorva, et al.
Publicado: (2008)

CRISPR/Cas12a Mediated Genome Editing To Introduce Amino Acid Substitutions into the Mechanosensitive Channel MscCG of Corynebacterium glutamicum
por: Krumbach, Karin, et al.
Publicado: (2019)

Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases
por: Brown, Alistair K., et al.
Publicado: (2009)

Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636
por: Bhowruth, Veemal, et al.
Publicado: (2008)

Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target
por: Gurcha, Sudagar S., et al.
Publicado: (2014)

The hydrolase LpqI primes mycobacterial peptidoglycan recycling
por: Moynihan, Patrick J., et al.
Publicado: (2019)

D152. Total Breast Reconstruction with Autologous Fat Transfer (AFT) And Reverse Expansion (ER): Experience with 2000 AFT-ER Breasts
por: Khouri, Roger K., et al.
Publicado: (2023)

Buckley-James Estimator of AFT Models with Auxiliary Covariates
por: Granville, Kevin, et al.
Publicado: (2014)

The ppm Operon Is Essential for Acylation and Glycosylation of Lipoproteins in Corynebacterium glutamicum
por: Mohiman, Niloofar, et al.
Publicado: (2012)

Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation
por: Cox, Jonathan A. G., et al.
Publicado: (2019)

Synthesis of α-Glucan in Mycobacteria Involves a Hetero-octameric Complex of Trehalose Synthase TreS and Maltokinase Pep2
por: Roy, Rana, et al.
Publicado: (2013)

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity
por: Stoop, Esther J M, et al.
Publicado: (2013)

Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria
por: Kermani, Ali A., et al.
Publicado: (2019)

Aft1 Nuclear Localization and Transcriptional Response to Iron Starvation Rely upon TORC2/Ypk1 Signaling and Sphingolipid Biosynthesis
por: Montellà-Manuel, Sandra, et al.
Publicado: (2023)

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2)
por: Zhang, Lu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e6k6u47vhakqsm8046gk6s7q2d