Genomic Knockout of Two Presumed Forelimb Tbx5 Enhancers Reveals They Are Nonessential for Limb Development

A standard approach in the identification of transcriptional enhancers is the use of transgenic animals carrying DNA elements joined to reporter genes inserted randomly in the genome. We examined elements near Tbx5, a gene required for forelimb development in humans and other vertebrates. Previous t...

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Detalles Bibliográficos
Autores principales: Cunningham, Thomas J., Lancman, Joseph J., Berenguer, Marie, Dong, P. Duc Si, Duester, Gregg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034701/
https://www.ncbi.nlm.nih.gov/pubmed/29898387
http://dx.doi.org/10.1016/j.celrep.2018.05.052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034701/
https://www.ncbi.nlm.nih.gov/pubmed/29898387
http://dx.doi.org/10.1016/j.celrep.2018.05.052

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