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MicroRNA molecular profiling identifies potential signaling pathways conferring resistance to chemoradiation in locally-advanced rectal adenocarcinoma

PURPOSE: There has been growing interest in using chemoradiation (CRT) for non-operative management of rectal cancer, and identifying patients who might benefit most from this approach is crucial. This study identified miRNAs (miRs) associated with clinical outcomes and treatment resistance by evalu...

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Detalles Bibliográficos
Autores principales: Pettit, Cory, Webb, Amy, Walston, Steve, Chatterjee, Moumita, Chen, Wei, Frankel, Wendy, Croce, Carlo, Williams, Terence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034754/
https://www.ncbi.nlm.nih.gov/pubmed/29988972
http://dx.doi.org/10.18632/oncotarget.25652